{
  "analytic": "protein-domain",
  "kind": "declared_analytical_or_constructed_example",
  "experimental_model_result": false,
  "panels": [
    {
      "kind": "heat",
      "matrix": [
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        [
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          12.0,
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          2.0,
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        ],
        [
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          12.0,
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          12.0,
          12.0,
          12.0,
          12.0,
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          2.0,
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          0.0,
          2.0,
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        ],
        [
          12.0,
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        ],
        [
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        ]
      ],
      "xlabel": "Constructed residue index",
      "ylabel": "Constructed alignment index",
      "unit": "Illustrative distance (A)"
    }
  ],
  "title": "Local and inter-domain uncertainty can differ",
  "assumptions": "Two fictional domains, 8 positions each. Within-domain value 2, between-domain 12, diagonal 0; NOT AlphaFold output or calibrated PAE.",
  "worked": "构造矩阵域内设2、域间设12、对角设0，用于区分局部与相对取向。它不是任何蛋白的PAE输出，也不能由颜色推导结合、功能或药效。",
  "source_ids": [
    "af2",
    "af3",
    "plddt"
  ],
  "formula_source": "Article equations and this versioned script",
  "diagram_nodes": [
    "序列 / 链 / 配体版本",
    "同源与模板语境",
    "结构预测及候选构象",
    "局部与域间置信信息",
    "几何比较 / 界面假设",
    "独立实验与功能结论"
  ]
}
