{
  "analytic": "retinal-foundation-models",
  "kind": "declared_analytical_or_constructed_example",
  "experimental_model_result": false,
  "panels": [
    {
      "kind": "line",
      "x": [
        0.001,
        0.0028805031446540877,
        0.004761006289308176,
        0.006641509433962264,
        0.008522012578616352,
        0.010402515723270441,
        0.012283018867924527,
        0.014163522012578617,
        0.016044025157232703,
        0.017924528301886792,
        0.01980503144654088,
        0.021685534591194967,
        0.023566037735849057,
        0.025446540880503143,
        0.027327044025157232,
        0.029207547169811318,
        0.031088050314465408,
        0.0329685534591195,
        0.03484905660377358,
        0.03672955974842767,
        0.03861006289308176,
        0.04049056603773585,
        0.042371069182389934,
        0.04425157232704402,
        0.04613207547169811,
        0.0480125786163522,
        0.049893081761006285,
        0.05177358490566038,
        0.053654088050314463,
        0.05553459119496855,
        0.057415094339622635,
        0.05929559748427673,
        0.061176100628930814,
        0.0630566037735849,
        0.064937106918239,
        0.06681761006289308,
        0.06869811320754717,
        0.07057861635220125,
        0.07245911949685534,
        0.07433962264150942,
        0.07622012578616352,
        0.07810062893081761,
        0.0799811320754717,
        0.08186163522012578,
        0.08374213836477987,
        0.08562264150943395,
        0.08750314465408804,
        0.08938364779874214,
        0.09126415094339622,
        0.09314465408805031,
        0.0950251572327044,
        0.09690566037735848,
        0.09878616352201257,
        0.10066666666666665,
        0.10254716981132075,
        0.10442767295597484,
        0.10630817610062893,
        0.10818867924528301,
        0.1100691823899371,
        0.11194968553459118,
        0.11383018867924527,
        0.11571069182389937,
        0.11759119496855346,
        0.11947169811320754,
        0.12135220125786163,
        0.12323270440251571,
        0.12511320754716979,
        0.12699371069182389,
        0.12887421383647799,
        0.13075471698113206,
        0.13263522012578616,
        0.13451572327044023,
        0.13639622641509433,
        0.13827672955974843,
        0.1401572327044025,
        0.1420377358490566,
        0.14391823899371067,
        0.14579874213836477,
        0.14767924528301885,
        0.14955974842767294,
        0.15144025157232704,
        0.15332075471698112,
        0.15520125786163522,
        0.1570817610062893,
        0.1589622641509434,
        0.16084276729559746,
        0.16272327044025156,
        0.16460377358490566,
        0.16648427672955973,
        0.16836477987421383,
        0.1702452830188679,
        0.172125786163522,
        0.17400628930817608,
        0.17588679245283018,
        0.17776729559748428,
        0.17964779874213835,
        0.18152830188679245,
        0.18340880503144652,
        0.18528930817610062,
        0.1871698113207547,
        0.1890503144654088,
        0.1909308176100629,
        0.19281132075471696,
        0.19469182389937106,
        0.19657232704402514,
        0.19845283018867924,
        0.2003333333333333,
        0.2022138364779874,
        0.2040943396226415,
        0.20597484276729558,
        0.20785534591194968,
        0.20973584905660375,
        0.21161635220125785,
        0.21349685534591192,
        0.21537735849056602,
        0.21725786163522012,
        0.2191383647798742,
        0.2210188679245283,
        0.22289937106918237,
        0.22477987421383647,
        0.22666037735849054,
        0.22854088050314464,
        0.23042138364779874,
        0.2323018867924528,
        0.2341823899371069,
        0.23606289308176098,
        0.23794339622641508,
        0.23982389937106915,
        0.24170440251572325,
        0.24358490566037735,
        0.24546540880503143,
        0.24734591194968553,
        0.2492264150943396,
        0.25110691823899367,
        0.25298742138364777,
        0.25486792452830187,
        0.25674842767295597,
        0.25862893081761007,
        0.2605094339622641,
        0.2623899371069182,
        0.2642704402515723,
        0.2661509433962264,
        0.26803144654088046,
        0.26991194968553456,
        0.27179245283018866,
        0.27367295597484276,
        0.27555345911949686,
        0.2774339622641509,
        0.279314465408805,
        0.2811949685534591,
        0.2830754716981132,
        0.2849559748427673,
        0.28683647798742135,
        0.28871698113207545,
        0.29059748427672955,
        0.29247798742138365,
        0.2943584905660377,
        0.2962389937106918,
        0.2981194968553459,
        0.3
      ],
      "series": [
        {
          "label": "PPV, Se=0.9 Sp=0.95",
          "y": [
            0.017699115044247773,
            0.04942860911587299,
            0.07928131309311155,
            0.10741896107418954,
            0.13398522262202314,
            0.15910815635053804,
            0.18290227418171584,
            0.20547028649054142,
            0.2269045842454549,
            0.24728850325379595,
            0.26669740699091415,
            0.28519961767517077,
            0.30285721983484415,
            0.3197267562845174,
            0.3358598329504217,
            0.3513036461747943,
            0.36610144384872695,
            0.3802929298628854,
            0.3939146198414671,
            0.40700015487068275,
            0.41958057889680767,
            0.4316845846091949,
            0.4433387319077683,
            0.45456764245617537,
            0.46539417331993843,
            0.47583957226658513,
            0.48592361694814873,
            0.49566473988439286,
            0.5050801409085375,
            0.51418588851865,
            0.5229970113910875,
            0.531527581152357,
            0.539790787368317,
            0.5477990055912723,
            0.5555638592033478,
            0.563096275706108,
            0.5704065380297133,
            0.5775043313682547,
            0.5843987859898492,
            0.5910985164194029,
            0.597611657347619,
            0.6039458965809793,
            0.610108505313322,
            0.6161063659696214,
            0.6219459978461416,
            0.6276335807477753,
            0.6331749768027485,
            0.6385757506165688,
            0.6438411879108769,
            0.6489763127784404,
            0.6539859036726918,
            0.6588745082387819,
            0.6636464570828998,
            0.6683058765674942,
            0.6728567007118538,
            0.6773026822701848,
            0.6816474030527543,
            0.6858942835497546,
            0.6900465919122396,
            0.6941074523396878,
            0.6980798529194333,
            0.7019666529593059,
            0.7057705898512945,
            0.7094942855008589,
            0.7131402523536234,
            0.7167108990485633,
            0.720208535724414,
            0.7236353790038702,
            0.7269935566781708,
            0.7302851121128737,
            0.7335120083939918,
            0.7366761322321638,
            0.7397792976411794,
            0.7428232494059259,
            0.7458096663536891,
            0.7487401644416938,
            0.7516162996728166,
            0.7544395708505244,
            0.7572114221832857,
            0.7599332457479671,
            0.7626063838210375,
            0.7652321310857895,
            0.7678117367231968,
            0.7703464063935077,
            0.7728373041151738,
            0.7752855540472716,
            0.7776922421811465,
            0.7800584179466289,
            0.7823850957378157,
            0.7846732563630736,
            0.786923848423623,
            0.7891377896247692,
            0.7913159680235928,
            0.7934592432166602,
            0.7955684474710908,
            0.7976443868021122,
            0.7996878420000275,
            0.8016995696093493,
            0.8036803028626766,
            0.8056307525717378,
            0.8075516079778745,
            0.8094435375641028,
            0.8113071898307626,
            0.8131431940366463,
            0.8149521609073853,
            0.81673468331277,
            0.8184913369145795,
            0.8202226807864123,
            0.8219292580069145,
            0.8236115962277331,
            0.8252702082174371,
            0.8269055923825895,
            0.8285182332670769,
            0.8301086020307519,
            0.8316771569083805,
            0.833224343649832,
            0.8347505959424008,
            0.8362563358161006,
            0.8377419740327274,
            0.8392079104594431,
            0.8406545344275933,
            0.8420822250774382,
            0.8434913516894358,
            0.8448822740026838,
            0.8462553425211017,
            0.8476108988078956,
            0.8489492757688294,
            0.8502707979247908,
            0.8515757816741287,
            0.8528645355451975,
            0.8541373604395416,
            0.8553945498661149,
            0.856636390166923,
            0.8578631607344502,
            0.8590751342212201,
            0.8602725767418162,
            0.8614557480676817,
            0.8626249018149948,
            0.8637802856259057,
            0.8649221413434072,
            0.8660507051800994,
            0.8671662078810937,
            0.8682688748812945,
            0.869358926457282,
            0.8704365778740116,
            0.8715020395265359,
            0.8725555170769433,
            0.8735972115867021,
            0.8746273196445901,
            0.8756460334903761,
            0.8766535411344224,
            0.8776500264733609,
            0.8786356694019921,
            0.8796106459215542,
            0.880575128244493,
            0.8815292848958682,
            0.8824732808115215,
            0.8834072774331221,
            0.8843314328002096,
            0.8852459016393441
          ]
        }
      ],
      "xlabel": "Hypothetical prevalence",
      "ylabel": "Positive predictive value",
      "logx": false,
      "logy": false
    },
    {
      "kind": "bar",
      "labels": [
        "Prevalence1%",
        "Prevalence20%"
      ],
      "series": [
        {
          "label": "True positive",
          "y": [
            90,
            1800
          ]
        },
        {
          "label": "False positive",
          "y": [
            495,
            400
          ]
        }
      ],
      "ylabel": "Expected count among 10000"
    }
  ],
  "title": "Identical classifier properties imply different workflow burden",
  "assumptions": "Hypothetical sensitivity 0.9,specificity0.95,N=10000; not RETFound performance, patient data,diagnosis or referral guidance.",
  "worked": "患病率1%：TP90、FP495、PPV≈0.153846；患病率20%：TP1800、FP400、PPV≈0.818182。这些只是期望计数。",
  "checks": {
    "ppv_01": 0.15384615384615385,
    "ppv_20": 0.8181818181818182
  },
  "generator_source_sha256": {
    "ops/datacenter/editorial_guides/science_figures.py": "01890ea429a67a880650c9b0602b1b66ed6ddeaa9704b7224897857a5f4803d7",
    "ops/datacenter/editorial_guides/deep_figures.py": "158969d9b1f5a4bd13906cf78dd71affc2692df9194593918059d861a6f59c85"
  },
  "source_ids": [
    "retfound",
    "clinical-oct",
    "arxiv-2012.07421"
  ],
  "formula_source": "Article equations and this versioned script",
  "diagram_nodes": [
    "定义任务和患者单位",
    "预训练与独立适配",
    "设备 / 机构 / 时间留出",
    "判别 / 校准 / 拒绝",
    "人工复核和流程终点",
    "前瞻性证据与版本"
  ]
}